Struma Ovarii Associated with Pseudo-Meigs' Syndrome and Elevated Serum CA 125

Background. Struma ovarii, presenting as pseudo-Meigs' syndrome with an elevated CA 125 level, is a rare condition. Case. A 65-year-old patient presented with ascites, hydrothorax, right ovarian mass, and elevated CA 125 level. These findings were suspicious for an ovarian malignancy. The mass...

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Bibliographic Details
Published in:Gynecologic oncology 2002-08, Vol.86 (2), p.231-234
Main Authors: Huh, Julie J., Montz, F.J., Bristow, Robert E.
Format: Article
Language:English
Subjects:
Aged
Ascites - etiology
Ascites - immunology
Biological and medical sciences
CA 125
CA-125 Antigen - blood
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Hydrothorax - etiology
Hydrothorax - immunology
Medical sciences
Meigs Syndrome - etiology
pseudo-Meigs' syndrome
struma ovarii
Struma Ovarii - complications
Struma Ovarii - immunology
Tumors
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Summary:Background. Struma ovarii, presenting as pseudo-Meigs' syndrome with an elevated CA 125 level, is a rare condition. Case. A 65-year-old patient presented with ascites, hydrothorax, right ovarian mass, and elevated CA 125 level. These findings were suspicious for an ovarian malignancy. The mass was removed and revealed struma ovarii, a specialized ovarian teratoma composed predominantly of mature thyroid tissue. In the setting of ascites and hydrothorax, the condition is known as pseudo-Meigs' syndrome. This is the second reported case in the English language literature of pseudo-Meigs' syndrome with an elevated CA 125 level resulting from struma ovarii. Conclusion. Struma ovarii is a rare cause of ascites, hydrothorax, and an elevated CA 125 level.
ISSN:0090-8258
1095-6859
DOI:10.1006/gyno.2002.6741