Kinetics of growth and fatty acid production of Rhodotorula glutinis

The effect of culture conditions, especially nitrogen/carbon (N/C) ratio and temperature, on acyl lipid profiles in the oleaginous yeast Rhodotorula glutinis NRRL Y 1091 have been investigated. Cultivation of the microorganism under N-limited conditions (N/C < 0.14 g/g) resulted in enhanced fatty...

Full description

Saved in:
Bibliographic Details
Published in:Applied microbiology and biotechnology 1992-04, Vol.37 (1), p.13-17
Main Authors: Granger, L.M, Perlot, P, Goma, G, Pareilleux, A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
Biotechnology
culture techniques
fatty acids
Fundamental and applied biological sciences. Psychology
growth
kinetics
Mission oriented research
Physiology and metabolism
Rhodotorula glutinis
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The effect of culture conditions, especially nitrogen/carbon (N/C) ratio and temperature, on acyl lipid profiles in the oleaginous yeast Rhodotorula glutinis NRRL Y 1091 have been investigated. Cultivation of the microorganism under N-limited conditions (N/C < 0.14 g/g) resulted in enhanced fatty acid (FA) cell content but a reduced relative amount of polyunsaturated fatty acids (PUFA). The maximal FA productivity was obtained for a 0.025 N/C ratio resulting from the arrangement between the specific rate of FA synthesis and the concentration of lipid-free biomass. Under nitrogen-non-limiting conditions, cells grown at lower temperatures had a higher PUFA content and the maximal productivity of alpha-linolenic acid was obtained by shifting the temperature of the culture from 30 degrees C to 25 degrees C.
ISSN:0175-7598
1432-0614
DOI:10.1007/bf00174195