Undifferentiated (embryonal) sarcoma of the liver in an adult patient with metastasis of the heart and brain

A 26-year-old woman with a tumor of the left liver lobe was admitted to the hospital. After incomplete resection of the tumor and histological diagnosis of an undifferentiated (embryonal) sarcoma of the liver a combination chemotherapy with ifosfamide and epidoxorubicine was started. 11 months later...

Full description

Saved in:
Bibliographic Details
Published in:The Clinical Investigator 1994-02, Vol.72 (3), p.209-212
Main Authors: REICHEL, C, FEHSKE, W, FISCHER, H. P, HARTLAPP, J. H
Format: Article
Language:English
Subjects:
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Brain Neoplasms - secondary
Combined Modality Therapy
Epirubicin - administration & dosage
Fatal Outcome
Female
Gastroenterology. Liver. Pancreas. Abdomen
Heart Neoplasms - diagnostic imaging
Heart Neoplasms - secondary
Humans
Ifosfamide - administration & dosage
Liver Neoplasms - drug therapy
Liver Neoplasms - pathology
Liver Neoplasms - surgery
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Neoplasm Recurrence, Local
Neoplasms, Germ Cell and Embryonal - drug therapy
Neoplasms, Germ Cell and Embryonal - secondary
Neoplasms, Germ Cell and Embryonal - surgery
Pericardium
Tumors
Ultrasonography
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 26-year-old woman with a tumor of the left liver lobe was admitted to the hospital. After incomplete resection of the tumor and histological diagnosis of an undifferentiated (embryonal) sarcoma of the liver a combination chemotherapy with ifosfamide and epidoxorubicine was started. 11 months later brain metastases were diagnosed. Routine ultrasound examination of the heart disclosed a pericardial tumor infiltrating the left atrium of the heart. After radiation therapy of the brain metastases the patient was treated with two cycles of high-dose ifosfamide and epidoxorubicin. Two years after diagnosis the patient developed signs of cardiac failure and died. Postmortem autopsy confirmed the local recurrence of the liver neoplasm and revealed its continuous spread to the pericardium via the diaphragm and infiltration of the left atrium.
ISSN:0941-0198
1432-1440
DOI:10.1007/BF00189313