Neurophysiological assessment of peripheral neuropathy in primary Sjögren's syndrome

Peripheral nervous system complications are rare in patients with primary Sjögren's syndrome. We investigated a group of six women aged 43-64 years who complained of pain and sensory symptoms. Conventional neurophysiological tests reflecting large nerve fiber function revealed normal motor cond...

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Bibliographic Details
Published in:The Clinical Investigator 1994-11, Vol.72 (11), p.822-829
Main Authors: DENISLIC, M, MEH, D
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Electrodiagnosis. Electric activity recording
Evaluation Studies as Topic
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Middle Aged
Nervous system
Pain - physiopathology
Peripheral Nervous System Diseases - etiology
Peripheral Nervous System Diseases - physiopathology
Sjogren's Syndrome - complications
Sjogren's Syndrome - physiopathology
Vibration
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Description
Summary:Peripheral nervous system complications are rare in patients with primary Sjögren's syndrome. We investigated a group of six women aged 43-64 years who complained of pain and sensory symptoms. Conventional neurophysiological tests reflecting large nerve fiber function revealed normal motor conduction in all patients, whereas sensory nerve action potentials were absent in two. On the other hand, quantitative thermometry and autonomic nerve function tests indicating small nerve fiber function were more sensitive in the assessment of nerve dysfunction; these showed abnormalities in all cases. Vibrametry showed dysfunctions in four patients. The latter methods possess great sensitivity in discovering sensory disturbances. Neurophysiological assessment of the sensory and autonomic nervous system demonstrating sensory neuropathy contributes to early diagnosis of primary Sjögren's syndrome.
ISSN:0941-0198
1432-1440
DOI:10.1007/BF00190735