Digitizing and signal averaging of left ventricular pressure signals using a dedicated radionuclide imaging system

A method for obtaining left ventricular (LV) volume curves, synchronized with average LV pressure (LVP) curves for calculation of LV contractility, is described. Multiple gated blood pool imaging was performed to calculate average LV volume curves. Simultaneously with this acquisition, LVPs and aort...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine 1987-01, Vol.13 (7), p.338-342
Main Authors: HERBST, C. P, DORMER, K. J, BRACKETT, D. J, WILSON, M. F, BARKAN, B, BUROW, R. D
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cardiovascular system
Dogs
Heart Rate
Heart Ventricles - diagnostic imaging
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Myocardial Contraction
Radionuclide Imaging
Radionuclide investigations
Signal Processing, Computer-Assisted
Sodium Pertechnetate Tc 99m
Stroke Volume
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Description
Summary:A method for obtaining left ventricular (LV) volume curves, synchronized with average LV pressure (LVP) curves for calculation of LV contractility, is described. Multiple gated blood pool imaging was performed to calculate average LV volume curves. Simultaneously with this acquisition, LVPs and aortic pressures were measured by indwelling catheters and recorded on an FM tape recorder. These signals were fed to the computer as image information and averaged and processed by the software developed for this purpose. Pressure resolution of the calibrated images was 4 mmHg/pixel when provision was made for a maximum pressure of 200 mmHg. A good correlation (r = 0.99) was obtained between the calculated peak LVPs and mean peak LVPs read from the chart recorder. The regression equation was: digitized peak LVP = 1.04 x chart recording--5.11 mmHg and the standard error of the estimate was 2.9 mmHg. Similar results were obtained with the aortic pressure (AP) measurements (digitized AP = 0.94 x chart recording + 6.37 mmHg, the standard error of the estimate was 3.8 mmHg). The digitized data also allowed the construction of pressure-volume loops for interpretation of ventricular contractility.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00252991