67Ga scan for evaluating response to therapy in malignant lymphoma

67Ga scintigrams in a patient with malignant lymphoma before and after chemotherapy are presented. 67Ga did not accumulate in the mostly necrotic mass with some viable cells. Negative uptake of 67Ga might reflect necrosis of the tumor; however, it is difficult to detect some residual tumor cells. Th...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine 1989, Vol.15 (12), p.800-812
Main Authors: KOIZUMI, K, OGATA, H, UCHIYAMA, G, ARAKI, T, HIHARA, T, MONZAWA, S, KACHI, K, MATSUSAKO, M
Format: Article
Language:English
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Bleomycin - administration & dosage
Cyclophosphamide - administration & dosage
Doxorubicin - administration & dosage
Gallium Radioisotopes
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymphoma - diagnostic imaging
Lymphoma - drug therapy
Male
Medical sciences
Methotrexate - administration & dosage
Middle Aged
Prednisolone - administration & dosage
Tomography, Emission-Computed, Single-Photon
Vincristine - administration & dosage
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Summary:67Ga scintigrams in a patient with malignant lymphoma before and after chemotherapy are presented. 67Ga did not accumulate in the mostly necrotic mass with some viable cells. Negative uptake of 67Ga might reflect necrosis of the tumor; however, it is difficult to detect some residual tumor cells. Therefore, negative uptake of 67Ga in the mass seen in X-ray CT may not be totally reliable evidence of eradication of viable tumor cells.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00255500