Per rectal thallium scintigraphy for the assessment of portosystemic shunt: an experimental study in the bile duct ligated rats

Bile duct ligated rats (n = 7) have been investigated for 6 months. Two patterns of evolution have been observed: (i) progressive development of cirrhosis and portosystemic shunt (detected by 201Tl per rectal scintigraphy) in three animals, (ii) repermeabilization of the biliary tract in four animal...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine 1989-09, Vol.15 (9), p.587-590
Main Authors: VAN MALDERGEM, L, JEGHERS, O, CADIERE, G, DE PREZ, C, HAM, H. R, PIEPSZ, A
Format: Article
Language:English
Subjects:
Administration, Rectal
Animals
Biological and medical sciences
Cholestasis - diagnostic imaging
Collateral Circulation
Disease Models, Animal
Gastroenterology. Liver. Pancreas. Abdomen
Imino Acids - administration & dosage
Liver Cirrhosis - diagnostic imaging
Liver Cirrhosis - etiology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Organotechnetium Compounds - administration & dosage
Other diseases. Semiology
Portal Vein - diagnostic imaging
Radionuclide Imaging
Rats
Rats, Inbred Strains
Technetium Tc 99m Lidofenin
Thallium - administration & dosage
Thallium Radioisotopes - administration & dosage
Venae Cavae - diagnostic imaging
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Summary:Bile duct ligated rats (n = 7) have been investigated for 6 months. Two patterns of evolution have been observed: (i) progressive development of cirrhosis and portosystemic shunt (detected by 201Tl per rectal scintigraphy) in three animals, (ii) repermeabilization of the biliary tract in four animals. Despite the small number of animals investigated, the 201Tl per rectal scintigraphy seems to be a good indicator of portosystemic shunt secondary to biliary cirrhosis.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00256934