Application of x-ray fluorescence to the study of iodine distribution and content in the thyroid

We have been developing an X-ray fluorescence system designed to determine iodine distribution and content in the thyroid. The X-ray fluorescence unit is composed of a 80 KV X-ray excitation beam and a Si(Li) semi-conductor detector. The angle between the X-ray beam and the axis of the detector is 2...

Full description

Saved in:
Bibliographic Details
Published in:European Journal of Nuclear Medicine 1981-01, Vol.6 (9), p.407-410
Main Authors: Aubert, B, Fragu, P, Di Paola, M, Rougier, P, Tubiana, M
Format: Article
Language:English
Subjects:
Humans
Iodine - metabolism
Radiography
Spectrometry, X-Ray Emission - instrumentation
Spectrometry, X-Ray Emission - methods
Thyroid Gland - diagnostic imaging
Thyroid Gland - metabolism
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We have been developing an X-ray fluorescence system designed to determine iodine distribution and content in the thyroid. The X-ray fluorescence unit is composed of a 80 KV X-ray excitation beam and a Si(Li) semi-conductor detector. The angle between the X-ray beam and the axis of the detector is 24 degree. Two single channel analyzers (SCA) are used, the first one corresponding to the K alpha peak and the other to the background. The SCA signals are digitised so that the two corresponding images may be processed using a computer. After subtracting the background, an image is obtained that represents the iodine distribution alone, and the iodine content of the whole thyroid or a part of it can be determined with a reproducibility of +/- 5%. A good correlation (r=0.98) between iodine chemical analysis and iodine fluorescence analysis was obtained for 13 patients.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00266431