Scintigraphic detection of inflammatory heart disease

Inflammatory diseases of the heart encompass myocarditis, endocarditis and pericarditis. This paper discusses the diagnostic potential of scintigraphy in these entities. In myocarditis, indium-111 antimyosin Fab imaging can visualize active myocyte damage and thus contribute substantially to the dia...

Full description

Saved in:
Bibliographic Details
Published in:European Journal of Nuclear Medicine 1994-07, Vol.21 (7), p.666-674
Main Authors: MORGUET, A. J, MUNZ, D. L, KREUZER, H, EMRICH, D
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiovascular system
Endocarditis - diagnostic imaging
Heart - diagnostic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Myocarditis - diagnostic imaging
Pericarditis - diagnostic imaging
Radioimmunodetection
Radionuclide investigations
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Inflammatory diseases of the heart encompass myocarditis, endocarditis and pericarditis. This paper discusses the diagnostic potential of scintigraphy in these entities. In myocarditis, indium-111 antimyosin Fab imaging can visualize active myocyte damage and thus contribute substantially to the diagnosis. Antimyosin uptake is also seen in a large subset of patients with dilated cardiomyopathy, indicating ongoing myocyte injury in these cases. In endocarditis, immunoscintigraphy using monoclonal technetium-99m-labelled antigranulocyte antibodies provides useful diagnostic information in patients with equivocal echocardiographic findings. Immunoscintigraphy seems to indicate the floridity of the inflammatory process in endocarditis and may be used to monitor antibiotic therapy. In pericarditis, the clinical value of scintigraphy has not been convincingly demonstrated.
ISSN:0340-6997
1619-7089
DOI:10.1007/bf00285591