Unusually long survival time after resection and irradiation of a brain metastasis from osteosarcoma

Cerebral metastases of osteosarcomas are rare. The cases published up to now have manifested only a short relapse-free period of survival. Intracranial filia generation must be anticipated if metastasis formation takes place in the lung. We report here on a young patient who underwent operation for...

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Bibliographic Details
Published in:Neurosurgical review 1990-01, Vol.13 (3), p.247-252
Main Authors: NIEDEGGEN, A, WEIS, J, MERTENS, R, ROÊTHER, J, BROÊCHELER, J
Format: Article
Language:English
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Bleomycin - administration & dosage
Brain Neoplasms - secondary
Brain Neoplasms - surgery
Brain Neoplasms - therapy
Child
Cisplatin - administration & dosage
Combined Modality Therapy
Cyclophosphamide - administration & dosage
Dactinomycin - administration & dosage
Diseases of the osteoarticular system
Doxorubicin - administration & dosage
Femoral Neoplasms - pathology
Humans
Interferon Type I - therapeutic use
Male
Medical sciences
Methotrexate - administration & dosage
Osteosarcoma - secondary
Osteosarcoma - surgery
Osteosarcoma - therapy
Prognosis
Tumors of striated muscle and skeleton
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Summary:Cerebral metastases of osteosarcomas are rare. The cases published up to now have manifested only a short relapse-free period of survival. Intracranial filia generation must be anticipated if metastasis formation takes place in the lung. We report here on a young patient who underwent operation for an intraparenchymal cerebral metastasis 76 months after amputation of the left leg due to an osteosarcoma chondroblasticum, and who is, at present, healthy, 13 months after resection. This unusually long survival time is attributed to the good neurological status before craniotomy, early diagnosis, and the improvement of the cytostatic therapy (COSS-80-scheme).
ISSN:0344-5607
1437-2320
DOI:10.1007/BF00313027