Cadmium, zinc and copper relationships in kidney and liver of humans exposed to environmental cadmium

Cadmium, copper and zinc have been determined in kidney cortex, kidney medulla and liver from 51 cadmium-polluted and 122 nonpolluted autopsied subjects. Liver cadmium and zinc were significantly higher in the cadmium-polluted subjects than in the nonpolluted subjects. Kidney cadmium, copper and zin...

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Bibliographic Details
Published in:Archives of toxicology 1987-04, Vol.59 (6), p.437-442
Main Authors: HONDA, R, NOGAWA, K
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Biological and medical sciences
Cadmium - adverse effects
Cadmium - metabolism
Child
Child, Preschool
Copper - metabolism
Environmental Pollutants - adverse effects
Environmental pollutants toxicology
Female
General aspects
Humans
Infant
Kidney - metabolism
Liver - metabolism
Male
Medical sciences
Middle Aged
Proteinuria - metabolism
Sex Factors
Toxicology
Zinc - metabolism
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Summary:Cadmium, copper and zinc have been determined in kidney cortex, kidney medulla and liver from 51 cadmium-polluted and 122 nonpolluted autopsied subjects. Liver cadmium and zinc were significantly higher in the cadmium-polluted subjects than in the nonpolluted subjects. Kidney cadmium, copper and zinc were lower in the cadmium-polluted subjects because of renal damage. Significant correlations of the three metals were found in the kidney. In the liver the correlation coefficients were significant only between cadmium and zinc.
ISSN:0340-5761
1432-0738
DOI:10.1007/bf00316211