Absence of mutagenic activity and a short-term toxicity study of beet pigments as food colorants

Beet colorant was tested for mutagenic activity in five S. typhimurium strains. The absence of mutagenic activity was found with or without S-9 rat liver fractions. Groups of six rats were fed red beet colorant preparations containing 2,000 ppm betalains in the diet for 7 days. No significant differ...

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Bibliographic Details
Published in:Archives of toxicology 1981-11, Vol.49 (1), p.93-98
Main Authors: Von Elbe, J.H, Schwartz, S.J
Format: Article
Language:English
Subjects:
Animals
Betalains
Body Weight - drug effects
Female
food additives
Food Coloring Agents - toxicity
food contamination
Lethal Dose 50
Male
Mutagenicity Tests
Pigments, Biological - toxicity
Quaternary Ammonium Compounds
Rats
Rats, Inbred Strains
Salmonella typhimurium - drug effects
Vegetables
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Summary:Beet colorant was tested for mutagenic activity in five S. typhimurium strains. The absence of mutagenic activity was found with or without S-9 rat liver fractions. Groups of six rats were fed red beet colorant preparations containing 2,000 ppm betalains in the diet for 7 days. No significant differences were noted in body weight gains, feed consumption, or gross pathological alterations compared to the controls. These preliminary toxicological results indicate the potential usage of betalain pigments as a food colorant, but further long term investigations are warranted.
ISSN:0340-5761
1432-0738
DOI:10.1007/BF00352077