Polymorphic reticulosis (lethal midline granuloma) and lymphomatoid granulomatosis: identical or distinct entities?

Two cases of polymorphic reticulosis were studied. Both cases had a fatal clinical course, that of the second case being rapid and progressive and ending 6 months after the onset of the disease with little demonstrable effect of steroid therapy. Biopsy material was obtained in both patients, and bot...

Full description

Saved in:
Bibliographic Details
Published in:Virchows Archiv A Pathological Anatomy and Histology 1981, Vol.390 (1), p.81-91
Main Authors: Stamenkovic, I, Toccanier, M F, Kapanci, Y
Format: Article
Language:English
Subjects:
Adult
Aged
Autopsy
Diagnosis, Differential
Female
Granuloma, Lethal Midline - diagnosis
Granuloma, Lethal Midline - pathology
Humans
Lung - pathology
Lymphomatoid Granulomatosis - diagnosis
Lymphomatoid Granulomatosis - pathology
Male
Pharynx - pathology
Skin - pathology
Tongue - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two cases of polymorphic reticulosis were studied. Both cases had a fatal clinical course, that of the second case being rapid and progressive and ending 6 months after the onset of the disease with little demonstrable effect of steroid therapy. Biopsy material was obtained in both patients, and both were submitted to a post-mortem examination. The first case showed typical angiocentric, angiodestructive, polymorphous lymphoreticular infiltrates, involving the pharyngeal region and the tongue. The second case demonstrated these same lesions in the midfacial region, the lungs and the skin. A possible identify between polymorphic reticulosis and lymphomatoid granulomatosis is discussed (because of the coexistence of identical lesions in the midfacial region and in the lung parenchyma in the second case). Wegener's granulomatosis in limited and disseminated forms and malignant lymphoma are considered in the differential diagnosis.
ISSN:0340-1227
1432-2307
DOI:10.1007/bf00443899