Timm-staining intensity is correlated with the density of Timm-positive presynaptic structures in the cerebral cortex of lizards

In cortical areas of the lizard, Podarcis hispanica, Timm staining reveals a distinct pattern of lamination. At the electron-microscope level, virtually all of the reaction product is located in the synaptic vesicles of Timm-positive boutons. Using linear-regression analysis, the area density of Tim...

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Bibliographic Details
Published in:Histochemistry 1987-01, Vol.86 (3), p.315-319
Main Authors: MARTINEZ-GUIJARRO, F. J, MOLOWNY, A, LOPEZ-GARCIA, C
Format: Article
Language:English
Subjects:
Anatomy
Animals
Biological and medical sciences
Central nervous system
Cerebral Cortex - ultrastructure
Densitometry
Fundamental and applied biological sciences. Psychology
Lizards - anatomy & histology
Microscopy, Electron
Regression Analysis
Staining and Labeling
Synaptic Vesicles - ultrastructure
Vertebrates: nervous system and sense organs
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Summary:In cortical areas of the lizard, Podarcis hispanica, Timm staining reveals a distinct pattern of lamination. At the electron-microscope level, virtually all of the reaction product is located in the synaptic vesicles of Timm-positive boutons. Using linear-regression analysis, the area density of Timm-positive bouton profiles as well as the numerical and volume density of stained vesicles were found to be closely correlated with the light-microscopic densitometric values obtained for each Timm-positive cortical zone. We discuss the possibility of estimating stereological electron-microscopic data parameters from densitometric measurements at the light-microscope level.
ISSN:0301-5564
1432-119X
DOI:10.1007/BF00490265