Angiotensin-like activity in resistance vessels. Immunocytochemical study in Chinese hamsters

Angiotensin II (ANG II) was localized immunocytochemically in kidney and various other organs of the chinese hamster. In the kidney ANG II-like activity was found in the epitheloid cells of the juxtaglomerular apparatus as well as in the media i.e. the smooth muscle cells of arcuate and interlobular...

Full description

Saved in:
Bibliographic Details
Published in:Histochemistry 1983-01, Vol.78 (1), p.61-70
Main Authors: Taugner, R, Bührle, C P, Ganten, D, Hackenthal, E, Hardegg, C, Hardegg, G, Nobiling, R, Unger, T
Format: Article
Language:English
Subjects:
Angiotensin II - immunology
Angiotensin II - metabolism
Animals
Cricetinae
Cricetulus
Female
Immunoenzyme Techniques
Kidney - blood supply
Kidney Glomerulus - blood supply
Male
Renin - physiology
Vascular Resistance
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Angiotensin II (ANG II) was localized immunocytochemically in kidney and various other organs of the chinese hamster. In the kidney ANG II-like activity was found in the epitheloid cells of the juxtaglomerular apparatus as well as in the media i.e. the smooth muscle cells of arcuate and interlobular arteries and afferent arterioles. ANG II-like activity was also observed in the medial muscle cells of resistance vessels in other organs and tissues such as submandibular gland and brown adipose tissue. The site of synthesis of ANG II needs to be investigated but the data point to the possibility of an intracellular function of ANG II in smooth muscle cells of blood vessels.
ISSN:0301-5564
1432-119X
DOI:10.1007/BF00491112