The activities of peroxisomal oxidases in periportal and perivenous zones of the rat liver acinus

Using a new biological microassay the activities of three peroxisomal oxidases in single microdissected periportal and perivenous zones of the liver acinus were measured. Whereas urate oxidase is homogeneously distributed through the acinus, the activities of D-aminoacid oxidase and alpha-hydroxyaci...

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Bibliographic Details
Published in:Histochemistry 1980, Vol.69 (1), p.95-99
Main Authors: Le Hir, M, Dubach, U C
Format: Article
Language:English
Subjects:
Alcohol Oxidoreductases - metabolism
Animals
D-Amino-Acid Oxidase - metabolism
Liver - enzymology
Male
Microbodies - enzymology
Rats
Urate Oxidase - metabolism
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Summary:Using a new biological microassay the activities of three peroxisomal oxidases in single microdissected periportal and perivenous zones of the liver acinus were measured. Whereas urate oxidase is homogeneously distributed through the acinus, the activities of D-aminoacid oxidase and alpha-hydroxyacid oxidase are respectively 1.80- and 2.71-fold higher in the periportal hepatocytes than in the perivenous hepatocytes.
ISSN:0301-5564
1432-119X
DOI:10.1007/BF00508370