Gastroesophageal reflux scintigraphy with radioactive capsules : a new technique for detection and quantitation of reflux

A new technique for performing quantitative gastroesophageal scintigraphy has been described. The method involves administration of radioactivity in capsule form into the stomach; the isotope is released after dissolution of the capsule. The mean time of onset of capsule breakage was 3.3 min (range...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine 1990, Vol.16 (4-6), p.345-348
Main Authors: SONI, P. S, SAROJINI, C, KRISHNA, B. A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Capsules
Esophagus
Gastroenterology. Liver. Pancreas. Abdomen
Gastroesophageal Reflux - diagnostic imaging
Humans
Medical sciences
Other diseases. Semiology
Radionuclide Imaging
Technetium Tc 99m Sulfur Colloid
Time Factors
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Summary:A new technique for performing quantitative gastroesophageal scintigraphy has been described. The method involves administration of radioactivity in capsule form into the stomach; the isotope is released after dissolution of the capsule. The mean time of onset of capsule breakage was 3.3 min (range 2-5 min) and complete dissolution occurred by 6.0 min (range 5-8 min). The appearance of isotope activity in the oesophagus by means of cine scintigraphy was quantified by PDP 11/34 computer (Gamma-11) in terms of percentage of gastroesophageal reflux (GER). In 15 healthy subjects, the percentage of reflux (mean +/- S.D.) in the lower, middle and upper oesophagus was found to be 1.25 +/- 0.67, 0.26 +/- 0.23 and 0.02 +/- 0.04 respectively. We have studied 52 patients using this technique, and results are encouraging.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00842790