Fatal fungal peritonitis in an adolescent on continuous ambulatory peritoneal dialysis: association with deferoxamine

An unusual case of Rhizopus microsporus (mucormycosis) fungal infection in a teenage boy on continuous ambulatory peritoneal dialysis is presented. Premortem cultures were negative and the patient developed a rapidly disseminated fatal infection. The patient was being treated with deferoxamine (DFO)...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 1989-01, Vol.3 (1), p.80-82
Main Authors: NAKAMURA, M, WEIL, W. B. JR, KAUFMAN, D. B
Format: Article
Language:English
Subjects:
Adolescent
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Deferoxamine - adverse effects
Emergency and intensive care: renal failure. Dialysis management
Glomerulonephritis, Membranous - complications
Humans
Intensive care medicine
Kidney Failure, Chronic - etiology
Kidney Failure, Chronic - therapy
Male
Medical sciences
Mucormycosis - etiology
Peritoneal Dialysis, Continuous Ambulatory
Peritonitis - etiology
Renal Dialysis
Rhizopus
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Summary:An unusual case of Rhizopus microsporus (mucormycosis) fungal infection in a teenage boy on continuous ambulatory peritoneal dialysis is presented. Premortem cultures were negative and the patient developed a rapidly disseminated fatal infection. The patient was being treated with deferoxamine (DFO) for iron and aluminum overload. An argument is made for a probable association between DFO and this fatal fungal infection in patients with end-stage renal disease.
ISSN:0931-041X
1432-198X
DOI:10.1007/BF00859631