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Atrial fibrillation following methylprednisolone pulse therapy

Two children, one with renal manifestations of systemic lupus erythematosus and the other with idiopathic nephrotic syndrome, were treated with methylprednisolone pulses. Neither had previous evidence of underlying cardiac disease. Within 24 h of pulse therapy, they complained of palpitations and de...

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Published in:Pediatric nephrology (Berlin, West) West), 1988-01, Vol.2 (1), p.29-31
Main Authors: UEDA, N, YOSHIKAWA, T, CHIHARA, M, KAWAGUCHI, S, NIINOMI, Y, YASAKI, T
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description Two children, one with renal manifestations of systemic lupus erythematosus and the other with idiopathic nephrotic syndrome, were treated with methylprednisolone pulses. Neither had previous evidence of underlying cardiac disease. Within 24 h of pulse therapy, they complained of palpitations and developed atrial fibrillation which reversed spontaneously or after anti-arrhythmic therapy. Subsequent serial electro- and echocardiograms were normal. We propose that the arrhythmias were a complication of steroid pulse therapy.
doi_str_mv 10.1007/bf00870376
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subjects Adolescent
Atrial Fibrillation - chemically induced
Biological and medical sciences
Child
Drug toxicity and drugs side effects treatment
Female
Humans
Lupus Nephritis - drug therapy
Male
Medical sciences
Methylprednisolone - administration & dosage
Methylprednisolone - adverse effects
Nephrotic Syndrome - drug therapy
Pharmacology. Drug treatments
Toxicity: cardiovascular system
title Atrial fibrillation following methylprednisolone pulse therapy
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