Ultrastructural evidence of myofibroblasts in pseudomalignant myositis ossificans

Seven cases of pseudomalignant ossifying myositis with a typical clinical symptomatology have been reported. None of the cases had experienced an injury. All the lesions were intramuscular and all of them showed a zonal arrangement. Electron microscopy in three cases allowed the demonstration of cel...

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Bibliographic Details
Published in:Virchows Archiv A Pathological Anatomy and Histology 1979-02, Vol.381 (2), p.189-203
Main Authors: Povysil, C., Matějovský, Z.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Child
Female
Humans
Macrophages - ultrastructure
Male
Microscopy, Electron
Middle Aged
Muscles - injuries
Muscles - ultrastructure
Myositis Ossificans - etiology
Myositis Ossificans - pathology
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Summary:Seven cases of pseudomalignant ossifying myositis with a typical clinical symptomatology have been reported. None of the cases had experienced an injury. All the lesions were intramuscular and all of them showed a zonal arrangement. Electron microscopy in three cases allowed the demonstration of cells showing morphological features of myofibroblasts and monocytic cells of the macrophage type. These previously unreported features together with the zonal pattern of the lesions indicate their reparative nature.
ISSN:0340-1227
1432-2307
DOI:10.1007/BF01257884