Comparison of perfusion lung scanning and angiography in the estimation of vascular obstruction in acute pulmonary embolism

To determine the relationships between perfusion scan defect and angiographic severity (Miller index) in acute pulmonary embolism, we analysed examinations obtained before and after thrombolytic therapy in 34 consecutive patients free from underlying cardiopulmonary disease. The overall agreement be...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine 1990-06, Vol.17 (6-8), p.315-319
Main Authors: MEYER, G, COLLIGNON, M. A, GUINET, F, JEFFREY, A. A, BARRITAULT, L, SORS, H
Format: Article
Language:English
Subjects:
Angiography
Biological and medical sciences
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Lung - diagnostic imaging
Male
Medical sciences
Middle Aged
Pulmonary Artery - diagnostic imaging
Pulmonary Embolism - diagnosis
Pulmonary Embolism - drug therapy
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radionuclide Imaging
Technetium Tc 99m Aggregated Albumin
Thrombolytic Therapy
Tissue Plasminogen Activator - therapeutic use
Urokinase-Type Plasminogen Activator - therapeutic use
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Summary:To determine the relationships between perfusion scan defect and angiographic severity (Miller index) in acute pulmonary embolism, we analysed examinations obtained before and after thrombolytic therapy in 34 consecutive patients free from underlying cardiopulmonary disease. The overall agreement between the two techniques was excellent (r = 0.82; mean absolute difference = 2.8%), although when embolic involvement was extensive (greater than 50% angiographic obstruction), the perfusion scan moderately underestimated (4%) the defect seen angiographically. These findings suggest that the pulmonary lung scan is a reliable method of assessing the initial pulmonary vascular obstruction as well as of quantifying any changes induced by or associated with the treatment.
ISSN:0340-6997
1619-7089
DOI:10.1007/bf01268022