Aspergillus endocarditis and myocarditis in a patient with the acquired immunodeficiency syndrome (AIDS) : a review of the literature

We report the post-mortem findings of the case of a 31-year-old male who, through sexual contacts with a female drug addict, was found to be HIV-positive and developed the acquired immunodeficiency syndrome (AIDS) 2 years later. He was treated for various opportunistic infections over the next 7 yea...

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Bibliographic Details
Published in:Virchows Archiv A Pathological Anatomy and Histopathology 1990-05, Vol.417 (3), p.255-259
Main Authors: COX, J. N, DI DIO, F, PIZZOLATO, G.-P, LERCH, R, POCHON, N
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome - complications
Adult
AIDS/HIV
Aspergillosis - complications
Aspergillosis - microbiology
Aspergillosis - pathology
Biological and medical sciences
Cardiology. Vascular system
Endocarditis - etiology
Endocarditis - microbiology
Endocarditis - pathology
Heart
Humans
Male
Medical sciences
Myocarditis - etiology
Myocarditis - microbiology
Myocarditis - pathology
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Summary:We report the post-mortem findings of the case of a 31-year-old male who, through sexual contacts with a female drug addict, was found to be HIV-positive and developed the acquired immunodeficiency syndrome (AIDS) 2 years later. He was treated for various opportunistic infections over the next 7 years when he presented with cardiac abnormalities and multiple cerebral lesions which were responsible for his death. The results revealed Aspergillus fumigatus endocarditis and myocarditis with mycotic thromboembolic extension to the brain, spleen, kidney and pancreas. We review the literature of Aspergillus infection in patients with AIDS and more specifically cardiac involvement with this pathogen.
ISSN:0174-7398
1432-2307
DOI:10.1007/BF01600142