End-tidal carbon dioxide pressure in neonates and infants measured by aspiration and flow-through capnography

In 25 anesthetized, intubated, artificially ventilated, and paralyzed healthy neonates and infants, end-tidal PCO2 (PETCO2) measured by remote multiplexed mass spectrometry was 1.86 +/- 1.58 mm Hg lower than arterial PCO2 (PaCO2). PETCO2 measured by a flow-through cuvette was 1.02 +/- 1.64 mm Hg low...

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Bibliographic Details
Published in:Journal of Clinical Monitoring 1991-10, Vol.7 (4), p.285-288
Main Authors: MICHAEL BADGWELL, J, HEAVNER, J. E
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Carbon Dioxide - analysis
Carbon Dioxide - blood
Emergency and intensive care: techniques, logistics
Humans
Infant
Infant, Newborn
Infrared Rays
Intensive care medicine
Intubation, Intratracheal
Mass Spectrometry
Medical sciences
Monitoring
Monitoring, Physiologic - instrumentation
Monitoring, Physiologic - methods
Respiration
Respiration, Artificial
Suction
Tidal Volume
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Summary:In 25 anesthetized, intubated, artificially ventilated, and paralyzed healthy neonates and infants, end-tidal PCO2 (PETCO2) measured by remote multiplexed mass spectrometry was 1.86 +/- 1.58 mm Hg lower than arterial PCO2 (PaCO2). PETCO2 measured by a flow-through cuvette was 1.02 +/- 1.64 mm Hg lower than PaCO2. The difference between the two methods of capnography was not significant. Values for PETCO2 obtained by mass spectrometry changed -0.43 +/- 1.43 mm Hg from baseline after 15 minutes of aspiration at a sample flow rate of 240 ml/min. Values for PETCO2 obtained with flow-through capnography changed -0.17 +/- 2.17 mm Hg from baseline after 15 minutes. In both methods, the changes from baseline in PETCO2 over time were not significant. These results suggest that both methods of capnography studied are reliable and may be used safely in neonates despite high sample flow rates and added apparatus dead space (0.6 ml for tracheal tubes less than or equal to 4.0 mm OD and 4.9 ml for tracheal tubes greater than 4.0 mm OD).
ISSN:0748-1977
2214-7330
1573-2614
DOI:10.1007/BF01619346