Accidental amikacin overdose in man: emergency therapy by extrarenal dialysis

Three accidental overdoses of amikacin (6, 6.5 and 8 times the normal dose) are reported. Emergency haemodialysis therapy was given and the serum levels monitored. No toxic effects were encountered. The need for such emergency haemodialysis seems to be limited to patients with impaired renal functio...

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Bibliographic Details
Published in:Infection 1979-07, Vol.7 (4), p.190-191
Main Authors: Flandrois, J P, Bouletreau, P, Auboyer, C, Ducluzeau, R, Muchada, R, Etienne, J
Format: Article
Language:English
Subjects:
Accidents
Adult
Aged
Amikacin - poisoning
Child
Emergencies
Humans
Kanamycin - analogs & derivatives
Poisoning - therapy
Renal Dialysis
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Summary:Three accidental overdoses of amikacin (6, 6.5 and 8 times the normal dose) are reported. Emergency haemodialysis therapy was given and the serum levels monitored. No toxic effects were encountered. The need for such emergency haemodialysis seems to be limited to patients with impaired renal function or to cases where little time has elapsed between intake and detection of overdose.
ISSN:0300-8126
1439-0973
DOI:10.1007/BF01640943