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Total body wash-out in patients with fulminant hepatitis

Two patients with fulminant hepatic necrosis and in stage IV coma were treated with a rapid infusion of refrigerated buffered albumin electrolyte solution combined with simultaneous total body wash-out in order to remove the circulating neurotoxins and to provide additional time for liver regenerati...

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Bibliographic Details
Published in:Infection 1977-01, Vol.5 (2), p.95-97
Main Authors: Balestrieri, G G, Manzillo, G, Spampinato, N, Tufano, R
Format: Article
Language:English
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Summary:Two patients with fulminant hepatic necrosis and in stage IV coma were treated with a rapid infusion of refrigerated buffered albumin electrolyte solution combined with simultaneous total body wash-out in order to remove the circulating neurotoxins and to provide additional time for liver regeneration. Both patients awoke from the coma following treatment. One patient recovered completely, the other died on the second day as a result of massive gastro-intestinal bleeding. The clinical value and the technical problems of the procedure are investigated.
ISSN:0300-8126
1439-0973
DOI:10.1007/BF01642088