Noninvasive diagnosis of renal allograft rejections--application of an information-theoretical model

This paper describes an information-theoretical model developed for detection of renal allograft rejection on the basis of various laboratory data. In this report the mathematical background of the model is described in detail and the rationale of its use is discussed. An example is given for the pr...

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Bibliographic Details
Published in:Klinische Wochenschrift 1988-01, Vol.66 (1), p.32-36
Main Authors: Heiss, H, Wild, W, Margreiter, R, Pfaller, W, Kotanko, P
Format: Article
Language:English
Subjects:
Biopsy, Needle
Computer Simulation
Graft Rejection
Humans
Kidney - pathology
Kidney Function Tests
Kidney Transplantation
Mathematical Computing
Microcomputers
Postoperative Complications - pathology
Probability
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Summary:This paper describes an information-theoretical model developed for detection of renal allograft rejection on the basis of various laboratory data. In this report the mathematical background of the model is described in detail and the rationale of its use is discussed. An example is given for the practical application of the model in kidney grafted patients. In the 30 patients of the test collective, seven rejection episodes were diagnosed by the clinicians and verified histologically. All seven rejection episodes were detected by the model, in the mean 2.4 days (median; 3 days) before the clinical diagnosis.
ISSN:0023-2173
1432-1440
DOI:10.1007/BF01735211