A double-blind, randomized, placebo-controlled, multi-center study of brofaromine in the treatment of post-traumatic stress disorder

A large multi-center, double-blind, parallel trial to assess the efficacy of brofaromine in the treatment of post traumatic stress disorder (PTSD) failed to show a significant difference between the brofaromine and placebo treatment groups. The placebo response rate in this study was higher than tha...

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Bibliographic Details
Published in:Psychopharmacologia 1995-12, Vol.122 (4), p.386-389
Main Authors: BAKER, D. G, DIAMOND, B. I, VANDER KOLK, B. A, KATZ, R, GILLETTE, G, HAMNER, M, KATZELNICK, D, KELLER, T, MELLMAN, T. A, PONTIUS, E, ROSENTHAL, M, TUCKER, P
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Double-Blind Method
Female
Humans
Male
Medical sciences
Middle Aged
Monoamine Oxidase Inhibitors - adverse effects
Monoamine Oxidase Inhibitors - therapeutic use
Neuropharmacology
Pharmacology. Drug treatments
Piperidines - adverse effects
Piperidines - therapeutic use
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Stress Disorders, Post-Traumatic - drug therapy
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Summary:A large multi-center, double-blind, parallel trial to assess the efficacy of brofaromine in the treatment of post traumatic stress disorder (PTSD) failed to show a significant difference between the brofaromine and placebo treatment groups. The placebo response rate in this study was higher than that in previously published double-blind, placebo-controlled studies of PTSD.
ISSN:0033-3158
1432-2072
DOI:10.1007/BF02246271