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Comparative study on the nuclear DNA content of leiomyoma, leiomyoblastoma and leiomyosarcoma of the stomach and small intestine

The nuclear DNA content of tumor cells in 5 leiomyomas, 4 leiomyoblastomas and 2 leiomyosarcomas of the stomach and 1 leiomyosarcoma of the small intestine was examined. From the viewpoint of nuclear DNA content, leiomyoblastoma was between leiomyoma and leiomyosarcoma. A definite difference in nucl...

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Published in:	Japanese journal of surgery 1981-11, Vol.11 (6), p.428-432
Main Authors:	Kimura, O, Kaibara, N, Tamura, H, Nishidoi, H, Okamoto, T, Koga, S
Format:	Article
Language:	English
Subjects:	Adult Aged Diagnosis, Differential DNA, Neoplasm - analysis Female Humans Intestinal Neoplasms - analysis Intestinal Neoplasms - diagnosis Intestine, Small Leiomyoma - analysis Leiomyoma - diagnosis Leiomyosarcoma - analysis Leiomyosarcoma - diagnosis Male Middle Aged Stomach Neoplasms - analysis Stomach Neoplasms - diagnosis
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container_end_page	432
container_issue	6
container_start_page	428
container_title	Japanese journal of surgery
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creator	Kimura, O Kaibara, N Tamura, H Nishidoi, H Okamoto, T Koga, S
description	The nuclear DNA content of tumor cells in 5 leiomyomas, 4 leiomyoblastomas and 2 leiomyosarcomas of the stomach and 1 leiomyosarcoma of the small intestine was examined. From the viewpoint of nuclear DNA content, leiomyoblastoma was between leiomyoma and leiomyosarcoma. A definite difference in nuclear DNA content exists among leiomyoma, leiomyoblastoma and leiomyosarcoma, and percentage of nuclei with a DNA content of 3 times or 4 times over the basic chromosome content represented good indices for distinguishing between benign and malignant conditions. A diagnosis of leiomyocarcinoma may be more accurate when over 80% of the nuclei have DNA content values over 3 times of basic nuclear DNA content and when over 50% exhibit more than 4 times of basic content.
doi_str_mv	10.1007/bf02469026
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From the viewpoint of nuclear DNA content, leiomyoblastoma was between leiomyoma and leiomyosarcoma. A definite difference in nuclear DNA content exists among leiomyoma, leiomyoblastoma and leiomyosarcoma, and percentage of nuclei with a DNA content of 3 times or 4 times over the basic chromosome content represented good indices for distinguishing between benign and malignant conditions. 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ispartof	Japanese journal of surgery, 1981-11, Vol.11 (6), p.428-432
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source	Springer Online Journal Archives
subjects	Adult Aged Diagnosis, Differential DNA, Neoplasm - analysis Female Humans Intestinal Neoplasms - analysis Intestinal Neoplasms - diagnosis Intestine, Small Leiomyoma - analysis Leiomyoma - diagnosis Leiomyosarcoma - analysis Leiomyosarcoma - diagnosis Male Middle Aged Stomach Neoplasms - analysis Stomach Neoplasms - diagnosis
title	Comparative study on the nuclear DNA content of leiomyoma, leiomyoblastoma and leiomyosarcoma of the stomach and small intestine
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