A New Cell Line Derived from Nickel Sulfide-Induced Rat Rhabdomyosarcoma

The morphological and chromosome characteristics of a cell line derived from a nickel sulfide-induced rhabdomyosarcoma in the Fisher strain of rats have been described. At the time of this report the cell line has undergone 59 passages and continues to exhibit the heteroploid trait and has retained...

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Bibliographic Details
Published in:In Vitro 1971-11, Vol.7 (3), p.158-160
Main Authors: N. Nath, Basrur, Parvathi K., R. Limebeer
Format: Article
Language:English
Subjects:
Animals
Cell growth
Cell Line
Cell lines
Chromosomes
Culture Techniques
Cultured cells
Diploidy
Fibroblasts - cytology
Karyotyping
Kidney cells
Mycoplasma
Neoplasm Transplantation
Neoplasms, Experimental - chemically induced
Neoplasms, Experimental - pathology
Nickel
Polyploidy
Rats
Rhabdomyosarcoma
Rhabdomyosarcoma - chemically induced
Rhabdomyosarcoma - pathology
Sulfides
Time Factors
Tumor cell line
Tumors
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Summary:The morphological and chromosome characteristics of a cell line derived from a nickel sulfide-induced rhabdomyosarcoma in the Fisher strain of rats have been described. At the time of this report the cell line has undergone 59 passages and continues to exhibit the heteroploid trait and has retained the malignant properties. This cell line, which lends itself to in vitro and in vivo (in rat) cultivation and carries easily recognizable chromosome markers, may prove to be useful in further research on tumor cells.
ISSN:0073-5655
1475-2689
DOI:10.1007/BF02617960