Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma

Renal cell carcinoma is an uncommon tumor in adults. Metastasis in the nasal fossa is rare, and can become apparent as a result of repeated epistaxis. We report a patient with renal cell carcinoma presenting with epistaxis secondary to a metastasis in the right nasal fossa. The primary tumor was tre...

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Bibliographic Details
Published in:Clinical & translational oncology 2006-04, Vol.8 (4), p.298-300
Main Authors: Cobo-Dols, Manuel, Alés-Díaz, Inmaculada, Villar-Chamorro, Ester, Gil-Calle, Silvia, Alcaide-García, Julia, Montesa-Pino, Alvaro, Gutiérrez-Calderón, Vanesa, Benavides-Orgaz, Manuel
Format: Article
Language:English
Subjects:
Adenocarcinoma, Clear Cell - pathology
Adenocarcinoma, Clear Cell - secondary
Adenocarcinoma, Clear Cell - therapy
Antimetabolites, Antineoplastic - therapeutic use
Antineoplastic Agents, Phytogenic - therapeutic use
Carcinoma, Renal Cell - pathology
Carcinoma, Renal Cell - secondary
Carcinoma, Renal Cell - therapy
Combined Modality Therapy
Embolization, Therapeutic
Epistaxis - etiology
Fatal Outcome
Fluorouracil - therapeutic use
Humans
Immunologic Factors - therapeutic use
Interferon-alpha - therapeutic use
Interleukin-2 - therapeutic use
Kidney Neoplasms - diagnosis
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Lung Neoplasms - secondary
Lung Neoplasms - surgery
Lymph Node Excision
Male
Middle Aged
Nasal Cavity
Nephrectomy
Nose Neoplasms - diagnosis
Nose Neoplasms - secondary
Nose Neoplasms - therapy
Orchiectomy
Pneumonectomy - methods
Radiotherapy, Adjuvant
Recombinant Proteins
Testicular Neoplasms - secondary
Testicular Neoplasms - surgery
Tomography, X-Ray Computed
Vinblastine - therapeutic use
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Summary:Renal cell carcinoma is an uncommon tumor in adults. Metastasis in the nasal fossa is rare, and can become apparent as a result of repeated epistaxis. We report a patient with renal cell carcinoma presenting with epistaxis secondary to a metastasis in the right nasal fossa. The primary tumor was treated with nephrectomy and the nasal fossa metastasis was treated successfully with embolization, chemoimmunotherapy, surgery, and radiotherapy. The presence of repeated epistaxis may very occasionally be the first symptom of renal cell carcinoma, and systemic treatment combined with local treatment may enable adequate control of the disease.
ISSN:1699-048X
1699-3055
DOI:10.1007/BF02664944