Effect ofABCG2,PPARGC1A,OLR1 andSCD1 gene polymorphism on estimated breeding values for functional and production traits in Polish Holstein-Friesian bulls

This study investigated the impact of 6 polymorphisms located in the ABCG2, PPARGC1A, OLR1 and SCD1 genes on estimated breeding values for milk production, longevity, somatic cell count and reproductive traits. The analysis was conducted on 453 Polish Holstein-Friesian bulls. Genotypes were identifi...

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Bibliographic Details
Published in:Journal of applied genetics 2009-06, Vol.50 (2), p.125-132
Main Authors: Komisarek, J., Dorynek, Z.
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Biomedical and Life Sciences
Human Genetics
Life Sciences
Microbial Genetics and Genomics
Original Article
Plant Genetics and Genomics
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Summary:This study investigated the impact of 6 polymorphisms located in the ABCG2, PPARGC1A, OLR1 and SCD1 genes on estimated breeding values for milk production, longevity, somatic cell count and reproductive traits. The analysis was conducted on 453 Polish Holstein-Friesian bulls. Genotypes were identified using PCR-RFLP, and haplotype inferences were performed for 3 linked mutations of PPARGC1A . The most significant associations were found between the A/C polymorphism located in exon 14 of ABCG2 and milk fat production traits as well as calving-to-first insemination interval, and between the T/C substitution in intron 9 of the PPARGC1A and non-return rate in heifers.
ISSN:1234-1983
2190-3883
DOI:10.1007/BF03195663