One-pot synthesis of functionalized α-acyloxythioamides from N-Protected a-amino acids as an acid component in the passerini reaction in an ionic liquid

N-Protected α-amino acids, prepared from benzoyl chlorides, KSCN and α-amino acids, were used as the acid component in the Passerini reaction, in an ionic liquid, to produce functionalized α-acyloxythioamides in 59–95% yields. The work-up procedure was fairly simple and the products did not require...

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Bibliographic Details
Published in:Journal of the Iranian Chemical Society 2011, Vol.8 (3), p.636-642
Main Authors: Yavari, I., Shahvelayati, A. S., Ghanbari, M., Ghazvini, M., Piltan, M.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Biochemistry
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Physical Chemistry
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Summary:N-Protected α-amino acids, prepared from benzoyl chlorides, KSCN and α-amino acids, were used as the acid component in the Passerini reaction, in an ionic liquid, to produce functionalized α-acyloxythioamides in 59–95% yields. The work-up procedure was fairly simple and the products did not require further purification.
ISSN:1735-207X
1735-2428
DOI:10.1007/BF03245894