The role of brachytherapy in the treatment of squamous cell carcinoma of the head and neck

Brachytherapy is a form of intensive local irradiation, allowing effective protection of surrounding structures with preservation of organ function and results in a favorable therapeutic ratio. It can be used alone, adjuvantly after surgery, and as a local boost in combination with external-beam rad...

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Published in:European archives of oto-rhino-laryngology 2016-02, Vol.273 (2), p.269-276
Main Authors: Wierzbicka, Małgorzata, Bartochowska, Anna, Strnad, Vratislav, Strojan, Primož, Mendenhall, William M., Harrison, Louis B., Rinaldo, Alessandra, Sahai, Puja, Wiegand, Susanne, Ferlito, Alfio
Format: Article
Language:English
Subjects:
Brachytherapy - methods
Carcinoma, Squamous Cell - radiotherapy
Head and Neck Neoplasms - radiotherapy
Head and Neck Surgery
Humans
Medicine
Medicine & Public Health
Neoplasm Recurrence, Local - radiotherapy
Neurosurgery
Otorhinolaryngology
Radiotherapy Dosage
Review Article
Squamous Cell Carcinoma of Head and Neck
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Summary:Brachytherapy is a form of intensive local irradiation, allowing effective protection of surrounding structures with preservation of organ function and results in a favorable therapeutic ratio. It can be used alone, adjuvantly after surgery, and as a local boost in combination with external-beam radiation therapy. This paper is a literature review on the role of brachytherapy in the management of head and neck cancers with a special emphasis on papers published in the last 5 years. Technical details, effectiveness and potential toxicities of brachytherapy when used in different combinations with other therapeutic modalities and tumor sites are presented. Brachytherapy is an attractive treatment option in the management of primary malignancies and recurrent tumors in previously irradiated areas of the head and neck. It is effective and safe, and results in good functional and oncological outcomes.
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-014-3332-8