Relationship between level CPAP titration, anthropometric variables, and drug-induced sleep endoscopy DISE

• Published in: European archives of oto-rhino-laryngology 2023-03, Vol.280 (3), p.1353-1359
• Main Authors: Merlano, Shirley Andrea Ramírez, Repetto, Giorgio Pio, Durán, Rodrigo Aliaga, Silva, Jorge Astudillo, Saldaña, Rodolfo Lugo
• Format: Article
• Language: English
• Subjects: Airway Obstruction - complications; Airway Obstruction - etiology; Endoscopy; Head and Neck; Head and Neck Surgery; Humans; Medicine; Medicine & Public Health; Neurosurgery; Otorhinolaryngology; Retrospective Studies; Sleep; Sleep Apnea Syndrome: From the pathogenesis to the last therapies; Sleep Apnea, Obstructive - complications; Sleep Apnea, Obstructive - diagnosis; Sleep Apnea, Obstructive - therapy
• ISSN: 0937-4477; 1434-4726
• DOI: 10.1007/s00405-022-07771-3

Introduction Subjects with palatal obstruction alone vs. multilevel obstruction on DISE had better outcomes after palate surgery. We asked ourselves if the therapeutic level positive airway pressure (PAP) titration could predict the level of airway obstruction and its complexity. Purpose The aim of this study was to identify possible relationships between therapeutic level of positive airway pressure initial titration and levels of collapse in drug-induced sleep endoscopy (DISE). A secondary objective was to establish the relationship the other variables and DISE. Methods We analyzed retrospective clinical histories between March 2020 to March 2022 of 37 patients with polysomnography or cardiorespiratory polygraphy studies and PAP initial titration who were taken to drug-induced sleep endoscopy. Sleep study data, anthropometric variables, and patterns of airway collapse during DISE were analyzed with PAP initial titration levels. Results Most of the patients with complex collapse had concentric velum collapse ( p