The early-stage diagnosis of albinic embryos by applying optical coherence tomography

Albinism is a kind of congenital disease of abnormal metabolism. Poecilia reticulata (guppy fish) is chosen as the model to study the development of albinic embryos as it is albinic, ovoviviparous and with short life period. This study proposed an imaging method for penetrative embryo investigation...

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Bibliographic Details
Published in:Optical review (Tokyo, Japan) Japan), 2013-09, Vol.20 (5), p.438-441
Main Authors: Yang, Bor-Wen, Wang, Shih-Yuan, Wang, Yu-Yen, Cai, Jyun-Jhang, Chang, Chung-Hao
Format: Article
Language:English
Subjects:
Atomic
Lasers
Microwaves
Molecular
Optical and Plasma Physics
Optical Devices
Optics
Photonics
Physics
Physics and Astronomy
Quantum Optics
Regular Paper
RF and Optical Engineering
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Summary:Albinism is a kind of congenital disease of abnormal metabolism. Poecilia reticulata (guppy fish) is chosen as the model to study the development of albinic embryos as it is albinic, ovoviviparous and with short life period. This study proposed an imaging method for penetrative embryo investigation using optical coherence tomography. By imaging through guppy mother’s reproduction purse, we found the embryo’s eyes were the early-developed albinism features. As human’s ocular albinism typically appear at about four weeks old, it is the time to determine if an embryo will grow into an albino.
ISSN:1340-6000
1349-9432
DOI:10.1007/s10043-013-0075-5