Evaluating the Holdup Time of Gas-Chromatographic Systems in Various Temperature Regimes by Using Recurrent Relations

The new algorithm for evaluating the holdup time of gas-chromatographic systems ( t 0 ) is considered. It is applicable at any temperature regimes of analysis not only isothermal, but also with linear temperature programming. It is based on the extrapolation of retention times of consecutive homolog...

Full description

Saved in:
Bibliographic Details
Published in:Chromatographia 2012-07, Vol.75 (13-14), p.767-777
Main Author: Zenkevich, Igor G.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Chemistry
Chemistry and Materials Science
Chromatography
Laboratory Medicine
Original
Pharmacy
Proteomics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The new algorithm for evaluating the holdup time of gas-chromatographic systems ( t 0 ) is considered. It is applicable at any temperature regimes of analysis not only isothermal, but also with linear temperature programming. It is based on the extrapolation of retention times of consecutive homologues (in particular, n -alkanes) with the evaluation of retention time of hypothetical homologue with zero number of carbon atoms in the molecule by using linear recurrent relations. It is shown that historically first method for evaluating t 0 using retention times ( t R ) of three consecutive homologues, proposed by Peterson and Hirsch (J Lipid Res 1:132–144, 1959), can be expanded onto temperature programming regimes after its modification by replacing t R values by their squares.
ISSN:0009-5893
1612-1112
DOI:10.1007/s10337-012-2260-2