Fe3O4 magnetic core coated by silver and functionalized with N-acetyl cysteine as novel nanoparticles in ferritin adsorption

• Published in: Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 2013-04, Vol.15 (4), Article 1564
• Main Authors: Akduman, Begüm, Uygun, Murat, Uygun, Deniz Aktaş, Antalík, Marián
• Format: Article
• Language: English
• Subjects: Characterization and Evaluation of Materials; Chemistry and Materials Science; Condensed matter: electronic structure, electrical, magnetic, and optical properties; Condensed matter: structure, mechanical and thermal properties; Cross-disciplinary physics: materials science; rheology; Electron, ion, and scanning probe microscopy; Exact sciences and technology; Inorganic Chemistry; Lasers; Magnetic properties and materials; Materials Science; Methods of nanofabrication; Nanotechnology; Optical Devices; Optics; Photonics; Physical Chemistry; Physics; Research Paper; Scanning probe microscopy: scanning tunneling, atomic force, scanning optical, magnetic force, etc; Small particles and nanoscale materials; Solid surfaces and solid-solid interfaces; Structure of solids and liquids; crystallography; Studies of specific magnetic materials; Surfaces and interfaces; thin films and whiskers (structure and nonelectronic properties)
• ISSN: 1388-0764; 1572-896X
• DOI: 10.1007/s11051-013-1564-y

A novel metal-chelate affinity matrix utilizing N -acetyl cysteine as a metal chelating agent was synthesized. For this, magnetic Fe 3 O 4 core was coated with silver by chemical reduction. Then, these magnetic silver nanoparticles were covered with N -acetyl cysteine, and Fe 3+ was chelated to this modified magnetic silver nanoparticle. These magnetic nanoparticles were characterized by SEM, AFM, EDX, and ESR analysis. Synthesized nanoparticles were spherical and average size is found to be 69 nm. Fe 3+ chelated magnetic silver nanoparticles were used for the adsorption of ferritin from its aqueous solution. Optimum conditions for the ferritin adsorption experiments were performed at pH 6.0 phosphate buffer and 25 °C of medium temperature and the maximum ferritin adsorption capacity is found to be 89.57 mg/g nanoparticle. Ferritin adsorption onto magnetic silver nanoparticles was increased with increasing ferritin concentration while adsorption capacity was decreased with increasing ionic strength. Affinity of the magnetic silver nanoparticles to the ferritin molecule was shown with SPR analysis. It was also observed that the adsorption capacity of the magnetic silver nanoparticles was not significantly changed after the five adsorption/desorption cycles.