Spectrophotometric assay of active components in medicinal formulations using the Vierordt method. I. Analysis of analgin-quinine and panadol extra

A method for the spectrophotometric assay of Analgin, caffeine, quinine hydrochloride, and paracetamol in two-component medicinal formulations was developed using a new criterion for selecting analytical wavelengths (AWL). Content calculations were performed using several sets of AWL. Model solution...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2008-10, Vol.42 (10), p.599-603
Main Authors: Vlasova, I. V., Shilova, A. V., Fokina, Yu. S.
Format: Article
Language:English
Subjects:
Medicine
Methods of Analysis and Process Control
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Structure of Chemical Compounds
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Summary:A method for the spectrophotometric assay of Analgin, caffeine, quinine hydrochloride, and paracetamol in two-component medicinal formulations was developed using a new criterion for selecting analytical wavelengths (AWL). Content calculations were performed using several sets of AWL. Model solutions were used to show that use of three sets of AWL decreases estimation errors for components in mixtures with both low and high contents. This method was used to analyze the medicinal formulations Panadol Extra and Analgin-quinine.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-009-0179-1