Modern Methods of Analysis of Carotenoids (Review)

Qualitative and quantitative methods of analysis of carotenoids that are used to analyze drugs, dietary supplements, and food products are reviewed. UV and visible spectrophotometry and chromatographic methods, e.g., thin-layer (TLC), high-performance liquid (HPLC), and supercritical fluid (SFC) chr...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2016-05, Vol.50 (2), p.96-107
Main Author: Finkel’shtein, E. I.
Format: Article
Language:English
Subjects:
Medicine
Methods of Analysis and Process Control
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Structure of Chemical Compounds
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Summary:Qualitative and quantitative methods of analysis of carotenoids that are used to analyze drugs, dietary supplements, and food products are reviewed. UV and visible spectrophotometry and chromatographic methods, e.g., thin-layer (TLC), high-performance liquid (HPLC), and supercritical fluid (SFC) chromatography, are discussed. The importance of using hybrid chromatography methods with IR, NMR, and mass-spectroscopic detectors is demonstrated. The dependence of carotenoid chromatographic separation parameters on sorbate polarity (dipole moment) in TLC, HPLC, and SFC is demonstrated for the first time.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-016-1405-2