Synthesis, Characterization and Antibacterial Screening of Diorganotin(IV) Complexes Derived From 2-[(4-Dimethylamino-Benzylidene)Amino]Phenol

Five organotin complexes have been derived from a Schiff base, 2-[(4-dimethylamino-benzylidene)amino] phenol. The synthesis of target compounds is confirmed by spectroscopic techniques: IR, 1 H NMR, and 13 C NMR. Activity of the initial Schiff base and its complexes has been tested with respect to v...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2017-05, Vol.51 (2), p.115-118
Main Authors: Rehman, Wajid, Haq, Sirajul, Rahim, Fazal, Khan, Salimullah, Waseem, Muhammad, Nawaz, Mohsan, Abid, Obaid-Ur-Rahman, Qursehi, Muhammad Tauseef, Guo, Cun-Yue
Format: Article
Language:English
Subjects:
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Summary:Five organotin complexes have been derived from a Schiff base, 2-[(4-dimethylamino-benzylidene)amino] phenol. The synthesis of target compounds is confirmed by spectroscopic techniques: IR, 1 H NMR, and 13 C NMR. Activity of the initial Schiff base and its complexes has been tested with respect to various bacterial strains, and the results obtained are quite promising against both Gram-positive and Gram-negative bacteria.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-017-1567-6