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Reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone derivatives and the properties of the obtained products
N ′-(4-Oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides and N ′-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides were synthesized by reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone or 2-methy...
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Published in: | Research on chemical intermediates 2011-10, Vol.37 (8), p.1009-1027 |
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cites | cdi_FETCH-LOGICAL-c288t-c5d2e6ae3fc0c5c87ecf4d11f7da9462e4b8f837752af7ba8d1c0730ce043f23 |
container_end_page | 1027 |
container_issue | 8 |
container_start_page | 1009 |
container_title | Research on chemical intermediates |
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creator | Vaickelionienė, Rita Mickevičius, Vytautas Mikulskienė, Gema Stasevych, Maryna Komarovska-Porokhnyavets, Olena Novikov, Volodymyr |
description | N
′-(4-Oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides and
N
′-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides were synthesized by reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone or 2-methyl-1,4-naphthoquinone. The alkylated analogues of the above products were obtained using ethyl iodide. The interaction of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 2,3-dichloro-1,4-naphthoquinone was followed by formation of
N
′-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides. All these compounds were characterized using
1
H,
13
C NMR, IR and mass spectra. Some of the new compounds were tested for the antimicrobial and antifungal activity. |
doi_str_mv | 10.1007/s11164-011-0306-y |
format | article |
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′-(4-Oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides and
N
′-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides were synthesized by reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone or 2-methyl-1,4-naphthoquinone. The alkylated analogues of the above products were obtained using ethyl iodide. The interaction of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 2,3-dichloro-1,4-naphthoquinone was followed by formation of
N
′-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides. All these compounds were characterized using
1
H,
13
C NMR, IR and mass spectra. Some of the new compounds were tested for the antimicrobial and antifungal activity.</description><identifier>ISSN: 0922-6168</identifier><identifier>EISSN: 1568-5675</identifier><identifier>DOI: 10.1007/s11164-011-0306-y</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Catalysis ; Chemistry ; Chemistry and Materials Science ; Inorganic Chemistry ; Physical Chemistry</subject><ispartof>Research on chemical intermediates, 2011-10, Vol.37 (8), p.1009-1027</ispartof><rights>Springer Science+Business Media B.V. 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c288t-c5d2e6ae3fc0c5c87ecf4d11f7da9462e4b8f837752af7ba8d1c0730ce043f23</citedby><cites>FETCH-LOGICAL-c288t-c5d2e6ae3fc0c5c87ecf4d11f7da9462e4b8f837752af7ba8d1c0730ce043f23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Vaickelionienė, Rita</creatorcontrib><creatorcontrib>Mickevičius, Vytautas</creatorcontrib><creatorcontrib>Mikulskienė, Gema</creatorcontrib><creatorcontrib>Stasevych, Maryna</creatorcontrib><creatorcontrib>Komarovska-Porokhnyavets, Olena</creatorcontrib><creatorcontrib>Novikov, Volodymyr</creatorcontrib><title>Reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone derivatives and the properties of the obtained products</title><title>Research on chemical intermediates</title><addtitle>Res Chem Intermed</addtitle><description>N
′-(4-Oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides and
N
′-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides were synthesized by reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone or 2-methyl-1,4-naphthoquinone. The alkylated analogues of the above products were obtained using ethyl iodide. The interaction of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 2,3-dichloro-1,4-naphthoquinone was followed by formation of
N
′-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides. All these compounds were characterized using
1
H,
13
C NMR, IR and mass spectra. Some of the new compounds were tested for the antimicrobial and antifungal activity.</description><subject>Catalysis</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Inorganic Chemistry</subject><subject>Physical Chemistry</subject><issn>0922-6168</issn><issn>1568-5675</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kE1OwzAQhS0EEqVwAHY5AAZP_uwuUcWfVAkJdR859pi4Knaw3UI4AccmoaxZjTTz3punj5BLYNfAGL-JAFCXlAFQVrCaDkdkBlUtaFXz6pjM2CLPaQ21OCVnMW4Yg0oINiPfLyhVst7FzJusov7TU6B9h27Y9kMIfmu1dUgLqmRofTfoIL-sxph92NRlcFVSJ_sudf59Z513mGkMdi-T3Y8a6XSWOsz64HsMyeLvl2nj2yTHXD2d9E6leE5OjNxGvPibc7K-v1svH-nq-eFpebuiKhciUVXpHGuJhVFMVUpwVKbUAIZruSjrHMtWGFFwXuXS8FYKDYrxgilkZWHyYk7gEKuCjzGgafpg32QYGmDNRLI5kGxGks1EshlGT37wxFHrXjE0G78Lbmz5j-kHID57DA</recordid><startdate>20111001</startdate><enddate>20111001</enddate><creator>Vaickelionienė, Rita</creator><creator>Mickevičius, Vytautas</creator><creator>Mikulskienė, Gema</creator><creator>Stasevych, Maryna</creator><creator>Komarovska-Porokhnyavets, Olena</creator><creator>Novikov, Volodymyr</creator><general>Springer Netherlands</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20111001</creationdate><title>Reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone derivatives and the properties of the obtained products</title><author>Vaickelionienė, Rita ; Mickevičius, Vytautas ; Mikulskienė, Gema ; Stasevych, Maryna ; Komarovska-Porokhnyavets, Olena ; Novikov, Volodymyr</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c288t-c5d2e6ae3fc0c5c87ecf4d11f7da9462e4b8f837752af7ba8d1c0730ce043f23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Catalysis</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Inorganic Chemistry</topic><topic>Physical Chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vaickelionienė, Rita</creatorcontrib><creatorcontrib>Mickevičius, Vytautas</creatorcontrib><creatorcontrib>Mikulskienė, Gema</creatorcontrib><creatorcontrib>Stasevych, Maryna</creatorcontrib><creatorcontrib>Komarovska-Porokhnyavets, Olena</creatorcontrib><creatorcontrib>Novikov, Volodymyr</creatorcontrib><collection>CrossRef</collection><jtitle>Research on chemical intermediates</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vaickelionienė, Rita</au><au>Mickevičius, Vytautas</au><au>Mikulskienė, Gema</au><au>Stasevych, Maryna</au><au>Komarovska-Porokhnyavets, Olena</au><au>Novikov, Volodymyr</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone derivatives and the properties of the obtained products</atitle><jtitle>Research on chemical intermediates</jtitle><stitle>Res Chem Intermed</stitle><date>2011-10-01</date><risdate>2011</risdate><volume>37</volume><issue>8</issue><spage>1009</spage><epage>1027</epage><pages>1009-1027</pages><issn>0922-6168</issn><eissn>1568-5675</eissn><abstract>N
′-(4-Oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides and
N
′-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides were synthesized by reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone or 2-methyl-1,4-naphthoquinone. The alkylated analogues of the above products were obtained using ethyl iodide. The interaction of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 2,3-dichloro-1,4-naphthoquinone was followed by formation of
N
′-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-1-phenyl-5-oxopyrrolidine-3-carbohydrazides. All these compounds were characterized using
1
H,
13
C NMR, IR and mass spectra. Some of the new compounds were tested for the antimicrobial and antifungal activity.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><doi>10.1007/s11164-011-0306-y</doi><tpages>19</tpages></addata></record> |
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source | Springer Nature |
subjects | Catalysis Chemistry Chemistry and Materials Science Inorganic Chemistry Physical Chemistry |
title | Reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone derivatives and the properties of the obtained products |
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