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Direct synthesis of cyanohydrin esters from aroyl chlorides using potassium hexacyanoferrate(II) as an eco-friendly cyanide source
A direct synthetic method for cyanohydrin esters from aroyl chlorides using potassium hexacyanoferrate(II) as an eco-friendly cyanide source and tributylphosphine as a promoter is described. This protocol has advantages of no use of strong toxic cyanating agents, high yield, and simple work-up proce...
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Published in: | Research on chemical intermediates 2015-05, Vol.41 (5), p.3147-3155 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | A direct synthetic method for cyanohydrin esters from aroyl chlorides using potassium hexacyanoferrate(II) as an eco-friendly cyanide source and tributylphosphine as a promoter is described. This protocol has advantages of no use of strong toxic cyanating agents, high yield, and simple work-up procedure. |
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ISSN: | 0922-6168 1568-5675 |
DOI: | 10.1007/s11164-013-1421-8 |