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Synthesis of 2-(4-methyl-1,3-thiazol-5-yl)ethyl esters of acridone carboxylic acids and evaluation of their antibacterial activity

2-(4-Methyl-1,3-thiazol-5-yl)ethyl acridone carboxylates were synthesized by the transesterification of the corresponding butyl esters. The kinetic characteristics of these reactions were determined, and the antimicrobial activity of a number of reaction products was investigated.

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Bibliographic Details
Published in:Russian chemical bulletin 2014-05, Vol.63 (5), p.1153-1158
Main Authors: Markovich, Yu. D., Kudryavtseva, T. N., Bogatyrev, K. V., Sysoev, P. I., Klimova, L. G., Nazarov, G. V.
Format: Article
Language:English
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Summary:2-(4-Methyl-1,3-thiazol-5-yl)ethyl acridone carboxylates were synthesized by the transesterification of the corresponding butyl esters. The kinetic characteristics of these reactions were determined, and the antimicrobial activity of a number of reaction products was investigated.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-014-0564-0