Natural compounds as a basis for the design of modulators of p53 activity

The present review summarizes data on compounds of natural origin increasing p53 expression in tumor cells. The main focus is on structures containing an indole core.

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Bibliographic Details
Published in:Russian chemical bulletin 2014-09, Vol.63 (9), p.1963-1975
Main Authors: Gureev, M. A., Davidovich, P. B., Tribulovich, V. G., Garabadzhiu, A. V.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Inorganic Chemistry
Organic Chemistry
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Summary:The present review summarizes data on compounds of natural origin increasing p53 expression in tumor cells. The main focus is on structures containing an indole core.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-014-0687-3