Synthesis of 6-thienyl-substituted 2-amino-3-cyanopyridines

An efficient method for the synthesis of 6-thienyl-substituted 2-amino-3-cyanopyridines by the ring transformation in the corresponding pyrimidines was developed. Further modification of the pyridines obtained under conditions of a room temperature aerobic Suzuki reaction in the presence of trans -b...

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Bibliographic Details
Published in:Russian chemical bulletin 2015-03, Vol.64 (3), p.689-694
Main Authors: Verbitskiy, E. V., Cheprakova, E. M., Pervova, M. G., Danagulyan, G. G., Rusinov, G. L., Chupakhin, O. N., Charushin, V. N.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
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Inorganic Chemistry
Organic Chemistry
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Summary:An efficient method for the synthesis of 6-thienyl-substituted 2-amino-3-cyanopyridines by the ring transformation in the corresponding pyrimidines was developed. Further modification of the pyridines obtained under conditions of a room temperature aerobic Suzuki reaction in the presence of trans -bis(dicyclohexylamine)palladium(II) acetate as a catalyst was studied
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-015-0920-8