A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)

• Published in: Chinese journal of integrative medicine 2012-03, Vol.18 (3), p.186-191
• Main Authors: Lu, Chuan-jian, Xiang, Yu, Xie, Xiu-li, Xuan, Mei-ling, He, Ze-hui
• Format: Article
• Language: English
• Subjects: Acupuncture, Ear; Adult; Anxiety - complications; Combined Modality Therapy; Depression - complications; Drugs, Chinese Herbal - adverse effects; Drugs, Chinese Herbal - therapeutic use; Female; Humans; Male; Medicine; Medicine & Public Health; Original Article; Outpatients; Pain Measurement; Psoriasis - complications; Psoriasis - drug therapy; Quality of Life; Severity of Illness Index; Single-Blind Method
• ISSN: 1672-0415; 1993-0402
• DOI: 10.1007/s11655-012-1020-3

Objective To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris. Methods A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI, Visual Analogue Scale (VAS), Dermatology Life Quality Index (DLQI), Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention. Results The PASI reduction rate in the treatment group was 74.4% (32/43), which was higher than that in the control group (36.6%, 15/41, P