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A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)
Objective To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris. Methods A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment...
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| Published in: | Chinese journal of integrative medicine 2012-03, Vol.18 (3), p.186-191 |
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| cites | cdi_FETCH-LOGICAL-c343t-9a6ea7e08bd48f2032cf262b264cf588a6ffcbe0107085f8d735305085eacc013 |
| container_end_page | 191 |
| container_issue | 3 |
| container_start_page | 186 |
| container_title | Chinese journal of integrative medicine |
| container_volume | 18 |
| creator | Lu, Chuan-jian Xiang, Yu Xie, Xiu-li Xuan, Mei-ling He, Ze-hui |
| description | Objective
To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris.
Methods
A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI, Visual Analogue Scale (VAS), Dermatology Life Quality Index (DLQI), Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention.
Results
The PASI reduction rate in the treatment group was 74.4% (32/43), which was higher than that in the control group (36.6%, 15/41,
P |
| doi_str_mv | 10.1007/s11655-012-1020-3 |
| format | article |
| fullrecord | <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1007_s11655_012_1020_3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>22466942</sourcerecordid><originalsourceid>FETCH-LOGICAL-c343t-9a6ea7e08bd48f2032cf262b264cf588a6ffcbe0107085f8d735305085eacc013</originalsourceid><addsrcrecordid>eNp9kMFqFTEUhoNYbK0-gBvJUhejJ8kkM3dZiq1CwY0uXA2ZTOY2ZSYZkox6u-veTRGKr6GgIPg4tuJbeOqoSzcnH-ec__zkJ-Qeg0cMoHqcGFNSFsB4wYBDIW6QHbZaiQJK4DeRVcWRmdwmt1M6AZCVAnmLbHNeKrUq-Q75tEej9l0Y3antqAk-xzAMiMn59WCLdnAe-1id0QPN0WENntYlDXOedHbW50TfuHxMpxRwnFyir-dhrSNCu6F6js7Mg440H9uopw26jK3z6PFbFabsFvdXzr91Fq3W9CDEETX0wc_3Xy4_nv84-_z924fLdxdXF18f3iFbvR6Svfvn3SUvD5682H9aHD0_fLa_d1QYUYpcrLSyurJQt11Z9xwENz1XvOWqNL2sa6363rQWGFRQy77uKiEFSGSrjQEmdglb7poYUoq2b6boRh03DYPmOv9myb_B_Jvr_BuBmvuLZprb0Xb_FH8DxwW-LCQc-bWNzUmYo8d__OfqL2hUmzc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)</title><source>Springer Nature</source><creator>Lu, Chuan-jian ; Xiang, Yu ; Xie, Xiu-li ; Xuan, Mei-ling ; He, Ze-hui</creator><creatorcontrib>Lu, Chuan-jian ; Xiang, Yu ; Xie, Xiu-li ; Xuan, Mei-ling ; He, Ze-hui</creatorcontrib><description>Objective
To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris.
Methods
A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI, Visual Analogue Scale (VAS), Dermatology Life Quality Index (DLQI), Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention.
Results
The PASI reduction rate in the treatment group was 74.4% (32/43), which was higher than that in the control group (36.6%, 15/41,
P
<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group
P
<0.01). With stratified analysis, there were significant differences between the PASI scores in the following subgroups: age 18–30, baseline PASI>10 and stable stage (
P
<0.05). DLQI decreased in both groups on some categories after treatment, but there were no significant differences between the two groups in SDS, SAS and VAS (
P
>0.05). No obvious adverse reactions were found in either group.
Conclusion
The therapeutic effect of auricular therapy combined with Optimized Yinxieling Formula was superior to Optimized Yinxieling Formula alone with no obvious adverse reaction.</description><identifier>ISSN: 1672-0415</identifier><identifier>EISSN: 1993-0402</identifier><identifier>DOI: 10.1007/s11655-012-1020-3</identifier><identifier>PMID: 22466942</identifier><language>eng</language><publisher>Heidelberg: Chinese Association of Traditional and Western Medicine</publisher><subject>Acupuncture, Ear ; Adult ; Anxiety - complications ; Combined Modality Therapy ; Depression - complications ; Drugs, Chinese Herbal - adverse effects ; Drugs, Chinese Herbal - therapeutic use ; Female ; Humans ; Male ; Medicine ; Medicine & Public Health ; Original Article ; Outpatients ; Pain Measurement ; Psoriasis - complications ; Psoriasis - drug therapy ; Quality of Life ; Severity of Illness Index ; Single-Blind Method</subject><ispartof>Chinese journal of integrative medicine, 2012-03, Vol.18 (3), p.186-191</ispartof><rights>Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c343t-9a6ea7e08bd48f2032cf262b264cf588a6ffcbe0107085f8d735305085eacc013</citedby><cites>FETCH-LOGICAL-c343t-9a6ea7e08bd48f2032cf262b264cf588a6ffcbe0107085f8d735305085eacc013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22466942$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Chuan-jian</creatorcontrib><creatorcontrib>Xiang, Yu</creatorcontrib><creatorcontrib>Xie, Xiu-li</creatorcontrib><creatorcontrib>Xuan, Mei-ling</creatorcontrib><creatorcontrib>He, Ze-hui</creatorcontrib><title>A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)</title><title>Chinese journal of integrative medicine</title><addtitle>Chin. J. Integr. Med</addtitle><addtitle>Chin J Integr Med</addtitle><description>Objective
To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris.
Methods
A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI, Visual Analogue Scale (VAS), Dermatology Life Quality Index (DLQI), Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention.
Results
The PASI reduction rate in the treatment group was 74.4% (32/43), which was higher than that in the control group (36.6%, 15/41,
P
<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group
P
<0.01). With stratified analysis, there were significant differences between the PASI scores in the following subgroups: age 18–30, baseline PASI>10 and stable stage (
P
<0.05). DLQI decreased in both groups on some categories after treatment, but there were no significant differences between the two groups in SDS, SAS and VAS (
P
>0.05). No obvious adverse reactions were found in either group.
Conclusion
The therapeutic effect of auricular therapy combined with Optimized Yinxieling Formula was superior to Optimized Yinxieling Formula alone with no obvious adverse reaction.</description><subject>Acupuncture, Ear</subject><subject>Adult</subject><subject>Anxiety - complications</subject><subject>Combined Modality Therapy</subject><subject>Depression - complications</subject><subject>Drugs, Chinese Herbal - adverse effects</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><subject>Outpatients</subject><subject>Pain Measurement</subject><subject>Psoriasis - complications</subject><subject>Psoriasis - drug therapy</subject><subject>Quality of Life</subject><subject>Severity of Illness Index</subject><subject>Single-Blind Method</subject><issn>1672-0415</issn><issn>1993-0402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kMFqFTEUhoNYbK0-gBvJUhejJ8kkM3dZiq1CwY0uXA2ZTOY2ZSYZkox6u-veTRGKr6GgIPg4tuJbeOqoSzcnH-ec__zkJ-Qeg0cMoHqcGFNSFsB4wYBDIW6QHbZaiQJK4DeRVcWRmdwmt1M6AZCVAnmLbHNeKrUq-Q75tEej9l0Y3antqAk-xzAMiMn59WCLdnAe-1id0QPN0WENntYlDXOedHbW50TfuHxMpxRwnFyir-dhrSNCu6F6js7Mg440H9uopw26jK3z6PFbFabsFvdXzr91Fq3W9CDEETX0wc_3Xy4_nv84-_z924fLdxdXF18f3iFbvR6Svfvn3SUvD5682H9aHD0_fLa_d1QYUYpcrLSyurJQt11Z9xwENz1XvOWqNL2sa6363rQWGFRQy77uKiEFSGSrjQEmdglb7poYUoq2b6boRh03DYPmOv9myb_B_Jvr_BuBmvuLZprb0Xb_FH8DxwW-LCQc-bWNzUmYo8d__OfqL2hUmzc</recordid><startdate>20120301</startdate><enddate>20120301</enddate><creator>Lu, Chuan-jian</creator><creator>Xiang, Yu</creator><creator>Xie, Xiu-li</creator><creator>Xuan, Mei-ling</creator><creator>He, Ze-hui</creator><general>Chinese Association of Traditional and Western Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20120301</creationdate><title>A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)</title><author>Lu, Chuan-jian ; Xiang, Yu ; Xie, Xiu-li ; Xuan, Mei-ling ; He, Ze-hui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c343t-9a6ea7e08bd48f2032cf262b264cf588a6ffcbe0107085f8d735305085eacc013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acupuncture, Ear</topic><topic>Adult</topic><topic>Anxiety - complications</topic><topic>Combined Modality Therapy</topic><topic>Depression - complications</topic><topic>Drugs, Chinese Herbal - adverse effects</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><topic>Outpatients</topic><topic>Pain Measurement</topic><topic>Psoriasis - complications</topic><topic>Psoriasis - drug therapy</topic><topic>Quality of Life</topic><topic>Severity of Illness Index</topic><topic>Single-Blind Method</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lu, Chuan-jian</creatorcontrib><creatorcontrib>Xiang, Yu</creatorcontrib><creatorcontrib>Xie, Xiu-li</creatorcontrib><creatorcontrib>Xuan, Mei-ling</creatorcontrib><creatorcontrib>He, Ze-hui</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Chinese journal of integrative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lu, Chuan-jian</au><au>Xiang, Yu</au><au>Xie, Xiu-li</au><au>Xuan, Mei-ling</au><au>He, Ze-hui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)</atitle><jtitle>Chinese journal of integrative medicine</jtitle><stitle>Chin. J. Integr. Med</stitle><addtitle>Chin J Integr Med</addtitle><date>2012-03-01</date><risdate>2012</risdate><volume>18</volume><issue>3</issue><spage>186</spage><epage>191</epage><pages>186-191</pages><issn>1672-0415</issn><eissn>1993-0402</eissn><abstract>Objective
To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris.
Methods
A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI, Visual Analogue Scale (VAS), Dermatology Life Quality Index (DLQI), Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention.
Results
The PASI reduction rate in the treatment group was 74.4% (32/43), which was higher than that in the control group (36.6%, 15/41,
P
<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group
P
<0.01). With stratified analysis, there were significant differences between the PASI scores in the following subgroups: age 18–30, baseline PASI>10 and stable stage (
P
<0.05). DLQI decreased in both groups on some categories after treatment, but there were no significant differences between the two groups in SDS, SAS and VAS (
P
>0.05). No obvious adverse reactions were found in either group.
Conclusion
The therapeutic effect of auricular therapy combined with Optimized Yinxieling Formula was superior to Optimized Yinxieling Formula alone with no obvious adverse reaction.</abstract><cop>Heidelberg</cop><pub>Chinese Association of Traditional and Western Medicine</pub><pmid>22466942</pmid><doi>10.1007/s11655-012-1020-3</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 1672-0415 |
| ispartof | Chinese journal of integrative medicine, 2012-03, Vol.18 (3), p.186-191 |
| issn | 1672-0415 1993-0402 |
| language | eng |
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| source | Springer Nature |
| subjects | Acupuncture, Ear Adult Anxiety - complications Combined Modality Therapy Depression - complications Drugs, Chinese Herbal - adverse effects Drugs, Chinese Herbal - therapeutic use Female Humans Male Medicine Medicine & Public Health Original Article Outpatients Pain Measurement Psoriasis - complications Psoriasis - drug therapy Quality of Life Severity of Illness Index Single-Blind Method |
| title | A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) |
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