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The role of hyaluronic acid in biomineralization

Hyaluronic acid has been extensively investigated due to intrinsic properties of natural origin and strong ability to bind ions in water. Hyaluronic acid is an excellent crystal modifier because its abundant negatively charged carboxyl groups can bind the cations protruding from the crystal lattice....

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Bibliographic Details
Published in:Frontiers of materials science 2012-12, Vol.6 (4), p.283-296
Main Authors: Chen, Zhen-Hua, Ren, Xiu-Li, Zhou, Hui-Hui, Li, Xu-Dong
Format: Article
Language:English
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Summary:Hyaluronic acid has been extensively investigated due to intrinsic properties of natural origin and strong ability to bind ions in water. Hyaluronic acid is an excellent crystal modifier because its abundant negatively charged carboxyl groups can bind the cations protruding from the crystal lattice. In this review, we mainly present the latest work focus on the role of hyaluronic acid in controlling the crystallization, breaking the symmetry of crystal, and the surface funtionalization of nanocrystals.
ISSN:2095-025X
2095-0268
DOI:10.1007/s11706-012-0182-4