Human plasma protein binding of water soluble flavonoids extracted from citrus peels

The human plasma protein binding of water soluble flavonoids in the peels of five spices of citrus fruits was studied by ultrafiltration combined with HPLC. The flavonoids were extracted separately by hot and cold water, and higher total flavonoid contents were detected in the former extracts than t...

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Bibliographic Details
Published in:Journal of Central South University 2014-07, Vol.21 (7), p.2645-2651
Main Authors: Zhao, Jin-yao, Li, Li, Jiao, Fei-peng, Ren, Feng-lian
Format: Article
Language:English
Subjects:
Engineering
Metallic Materials
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Summary:The human plasma protein binding of water soluble flavonoids in the peels of five spices of citrus fruits was studied by ultrafiltration combined with HPLC. The flavonoids were extracted separately by hot and cold water, and higher total flavonoid contents were detected in the former extracts than the latter ones. All the extracts show significant scavenging abilities to both ABTS and DPPH free radicals, which indicates the health benefits of the water extracts of citrus fruits peels. For DPPH radical, the IC 50 values of hot extract follow as Navel orange (NO)≈Mandarin orange (MO)< Lemon (LE)< Lo tangerine (LO)< Pomelo (PO), while the rank is NO< PO
ISSN:2095-2899
2227-5223
DOI:10.1007/s11771-014-2225-8