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Trends in Utilization of Third-Line Therapies for Non-neurogenic Overactive Bladder: Sacral Neuromodulation, Peripheral Tibial Nerve Stimulation, and Intradetrusor OnabotulinumtoxinA
Purpose of Review To report on current and emerging trends in the use of third-line therapies for non-neurogenic overactive bladder (OAB). Recent findings The use of third-line therapies for OAB has been steadily increasing, but it appears that only a small percentage of OAB patients receive them. R...
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Published in: | Current bladder dysfunction reports 2018-06, Vol.13 (2), p.25-30 |
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description | Purpose of Review
To report on current and emerging trends in the use of third-line therapies for non-neurogenic overactive bladder (OAB).
Recent findings
The use of third-line therapies for OAB has been steadily increasing, but it appears that only a small percentage of OAB patients receive them. Recent research has found an increased risk of dementia associated with cumulative use of anticholinergic medications, including OAB antimuscarinic medications. Cost-effective analyses suggest that these third-line therapies may be worth considering prior to medications.
Summary
Research and efforts to improve adherence to current OAB guidelines are needed to increase their use by patients with refractory OAB. Whether or not the therapies we presently consider third line should actually be second line for some of our patients remains to be determined. |
doi_str_mv | 10.1007/s11884-018-0462-7 |
format | article |
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To report on current and emerging trends in the use of third-line therapies for non-neurogenic overactive bladder (OAB).
Recent findings
The use of third-line therapies for OAB has been steadily increasing, but it appears that only a small percentage of OAB patients receive them. Recent research has found an increased risk of dementia associated with cumulative use of anticholinergic medications, including OAB antimuscarinic medications. Cost-effective analyses suggest that these third-line therapies may be worth considering prior to medications.
Summary
Research and efforts to improve adherence to current OAB guidelines are needed to increase their use by patients with refractory OAB. Whether or not the therapies we presently consider third line should actually be second line for some of our patients remains to be determined.</description><identifier>ISSN: 1931-7212</identifier><identifier>EISSN: 1931-7220</identifier><identifier>DOI: 10.1007/s11884-018-0462-7</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Geriatrics/Gerontology ; Gynecology ; Medicine ; Medicine & Public Health ; Overactive Bladder (U Lee and S Adelstein ; Section Editors ; Topical Collection on Overactive Bladder ; Urology</subject><ispartof>Current bladder dysfunction reports, 2018-06, Vol.13 (2), p.25-30</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c266t-9f7c8aad26e58c7df4a8960003e96107026880fc16232e6da24fd3f56dd8ca7f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Kirby, Anna C.</creatorcontrib><creatorcontrib>Kellogg, Elizabeth S.</creatorcontrib><title>Trends in Utilization of Third-Line Therapies for Non-neurogenic Overactive Bladder: Sacral Neuromodulation, Peripheral Tibial Nerve Stimulation, and Intradetrusor OnabotulinumtoxinA</title><title>Current bladder dysfunction reports</title><addtitle>Curr Bladder Dysfunct Rep</addtitle><description>Purpose of Review
To report on current and emerging trends in the use of third-line therapies for non-neurogenic overactive bladder (OAB).
Recent findings
The use of third-line therapies for OAB has been steadily increasing, but it appears that only a small percentage of OAB patients receive them. Recent research has found an increased risk of dementia associated with cumulative use of anticholinergic medications, including OAB antimuscarinic medications. Cost-effective analyses suggest that these third-line therapies may be worth considering prior to medications.
Summary
Research and efforts to improve adherence to current OAB guidelines are needed to increase their use by patients with refractory OAB. Whether or not the therapies we presently consider third line should actually be second line for some of our patients remains to be determined.</description><subject>Geriatrics/Gerontology</subject><subject>Gynecology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Overactive Bladder (U Lee and S Adelstein</subject><subject>Section Editors</subject><subject>Topical Collection on Overactive Bladder</subject><subject>Urology</subject><issn>1931-7212</issn><issn>1931-7220</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kN1OAjEQhTdGExF9AO_6AFbbLnS73iHxh4SACXC9Kf3BkqUl0y5RH8zncwHDpVdzkvnOmcnJsltK7ikhxUOkVIgeJlRg0uMMF2dZh5Y5xQVj5PykKbvMrmJcE9In_ZJ1sp85GK8jch4tkqvdt0wueBQsmn840HjsvGmlAbl1JiIbAE2Cx940EFbGO4Wmu3apktsZ9FRLrQ08oplUIGs02VOboJv6kHqH3g247T6sRnO3dAcEWuMsuc0Jkl6jkU8gtUnQxPbi1MtlSE3tfLNJ4dP5wXV2YWUdzc3f7GaLl-f58A2Pp6-j4WCMFeM84dIWSkipGTd9oQpte1KUnBCSm5JTUhDGhSBWUc5yZriWrGd1bvtca6FkYfNuRo-5CkKMYGy1BbeR8FVRUu2Lr47FV23x1b74qmg97OiJLetXBqp1aMC3b_5j-gWy1YtH</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Kirby, Anna C.</creator><creator>Kellogg, Elizabeth S.</creator><general>Springer US</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20180601</creationdate><title>Trends in Utilization of Third-Line Therapies for Non-neurogenic Overactive Bladder: Sacral Neuromodulation, Peripheral Tibial Nerve Stimulation, and Intradetrusor OnabotulinumtoxinA</title><author>Kirby, Anna C. ; Kellogg, Elizabeth S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c266t-9f7c8aad26e58c7df4a8960003e96107026880fc16232e6da24fd3f56dd8ca7f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Geriatrics/Gerontology</topic><topic>Gynecology</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Overactive Bladder (U Lee and S Adelstein</topic><topic>Section Editors</topic><topic>Topical Collection on Overactive Bladder</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kirby, Anna C.</creatorcontrib><creatorcontrib>Kellogg, Elizabeth S.</creatorcontrib><collection>CrossRef</collection><jtitle>Current bladder dysfunction reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kirby, Anna C.</au><au>Kellogg, Elizabeth S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trends in Utilization of Third-Line Therapies for Non-neurogenic Overactive Bladder: Sacral Neuromodulation, Peripheral Tibial Nerve Stimulation, and Intradetrusor OnabotulinumtoxinA</atitle><jtitle>Current bladder dysfunction reports</jtitle><stitle>Curr Bladder Dysfunct Rep</stitle><date>2018-06-01</date><risdate>2018</risdate><volume>13</volume><issue>2</issue><spage>25</spage><epage>30</epage><pages>25-30</pages><issn>1931-7212</issn><eissn>1931-7220</eissn><abstract>Purpose of Review
To report on current and emerging trends in the use of third-line therapies for non-neurogenic overactive bladder (OAB).
Recent findings
The use of third-line therapies for OAB has been steadily increasing, but it appears that only a small percentage of OAB patients receive them. Recent research has found an increased risk of dementia associated with cumulative use of anticholinergic medications, including OAB antimuscarinic medications. Cost-effective analyses suggest that these third-line therapies may be worth considering prior to medications.
Summary
Research and efforts to improve adherence to current OAB guidelines are needed to increase their use by patients with refractory OAB. Whether or not the therapies we presently consider third line should actually be second line for some of our patients remains to be determined.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s11884-018-0462-7</doi><tpages>6</tpages></addata></record> |
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subjects | Geriatrics/Gerontology Gynecology Medicine Medicine & Public Health Overactive Bladder (U Lee and S Adelstein Section Editors Topical Collection on Overactive Bladder Urology |
title | Trends in Utilization of Third-Line Therapies for Non-neurogenic Overactive Bladder: Sacral Neuromodulation, Peripheral Tibial Nerve Stimulation, and Intradetrusor OnabotulinumtoxinA |
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